Type regedit, and click OK to open the Registry.Use the Windows key + R keyboard shortcut to open the Run command.It's recommended to make a full backup of your PC before proceeding. Warning: This is a friendly reminder that editing the Registry is risky, and it can cause irreversible damage to your installation if you don't do it correctly. If you're using a third-party antivirus on Windows 10 build 17672 or later, you can make sure that Windows Defender Antivirus stays disabled by making changes to the Registry.
How to keep Windows Defender Antivirus disabled on Windows 10 In this Windows 10 guide, we'll walk you through the steps to ensure that Windows Defender Antivirus stays disabled as you install a different antivirus product that doesn't run as a protected process.